Treatment of elevated histamine and uric acid levels

摘要

Compounds having the general formula <IMAGE> (the meanings of R1, R2, R3, R4 and R5 are indicated hereinafter) and the pharmaceutically acceptable salts and esters thereof exhibit strong activities in inhibiting histidine decarboxylase and xanthine oxidase and are useful for treating elevated histamine and uric acid levels. One example is the compound of the formula <IMAGE>