WERKWIJZE VOOR DE BEREIDING VAN 5-THIAZOLYL- METHYLAMINEN EN ZOUTEN DAARVAN, ALSMEDE EEN WERKWIJZE VOOR DE BEREIDING VAN PREPARATEN DIE ZE BEVATTEN.

摘要

1526038 Thiazole derivatives ROUSSELUCLAF 13 Sept 1976 [12 Sept 1975 31 March 1976] 37770/76 Heading C2C Novel compounds of Formula I (in which R1 represents an alkyl radical containing from 1 to 6 carbon atoms, and R2 and R3, which may be the same or different, each represents a hydrogen atom, an alkyl group containing from 1 to 6 carbon atoms, or a hydroxyl-substituted alkyl group containing from 1 to 6 carbon atoms, or alternatively R2 and R3 with the nitrogen atom to which they are bonded together form a saturated heterocycle containing 1 or 2 nitrogen atoms and which moreover optionally bears an alkyl substituent containing from 1 to 4 carbon atoms) and acid addition salts thereof are prepared from compounds of Formula II wherein X is Br or Cl by standard methods. Starting materials of Formula II above and intermediates are also prepared. Pharmaceutical compositions in conventional forms and having antilipoic and antiglycaemic activity comprise an above novel compound and a carrier or diluent.