摘要 |
NEW MATERIAL:A compound expressed by formula I (n is 8-22; R and R1 are alkoxy or H). USE:Useful in assembling a light-responsive liposome system for medicine or agricultural chemical. The compound expressed by formula I is a compound containing a m-methoxybenzyl group which is a highly efficient light accepting group in the end of hydrophobic part and can be synthesized in good efficiency. PREPARATION:An acid chloride expressed by formula II is reacted with m- methoxybenzyl alcohol (derivative) expressed by formula III in a polar aprotic solvent and then the reaction product is subjected to after-treatment with water to afford a compound expressed by formula IV. Then the compound expressed by formula IV is condensed with phosphatidylglycerol expressed by formula V, e.g. by a method dissolving the compound expressed by formula IV, 4- dimethylaminopyridine and dicyclohexylcarbodiimide which is a condensing agent in chloroform, adding CdCl2 salt of compound expressed by formula V thereto and stirring the mixture. |