发明名称 CHROMONE DERIVATIVES
摘要 <p>1417462 Chromone derivatives TAKEDA YAHUHIN KOGYO KK 12 April 1973 [12 April 1972] 14972/75 Divided out of 1417461 Heading C2C The invention comprises compounds having the general formula wherein n is 0 or 1; m is 0, 1 or 2, when each of the R radicals is halogen, nitro, straight or branched C 1 to C 6 alkyl, C 3 to C 6 cycloalkyl, butadienylene (-CH = CH-CH = CH-) which forms a benzene ring with any two adjacent carbon atoms at positions 5, 6, 7 and 8, -COOR<SP>1</SP>, (where R<SP>1</SP> is hydrogen, C 1 to C 3 alkyl or aralkyl) carboxamide (optionally substituted by alkyl or aralkyl), or amino (optionally substituted by R<SP>11</SP>CO-, where R<SP>11</SP> is straight or branched alkyl or aryl), or C 1 to C 3 alkyl, aralkyl or aryl; and m is 0 or 1 when each R is hydroxy, C 1 to C 4 alkoxy or R<SP>111</SP>COO-, where R<SP>111</SP> is straight or branched alkyl or aryl. The compounds of the invention may be prepared by reacting a compound of the formula with hydroxylamine or cyanoacetic acid. The compounds of the invention exhibit pharmaceutical activity.</p>
申请公布号 CA1006160(A) 申请公布日期 1977.03.01
申请号 CA19730168432 申请日期 1973.04.11
申请人 TAKEDA CHEMICAL INDUSTRIES, LTD. 发明人 NOHARA, AKIRA;UMETANI, TOMONOBU;SANNO, YASUSHI
分类号 C07D405/04;A61K31/352;C07D257/04;C07D311/22;C07D311/92;C07D405/06 主分类号 C07D405/04
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