Process for the preparation of taurine-conjugated bile acids.

摘要

Process for the preparation of taurine-conjugated biliary acids of general formula (I): (Y-NH-CH2-CH2-SO3)1M (I> where Y is the acyl of a biliary acid selected from the group consisting of ursodeoxycholic, chenodeoxycholic, lithocholic, 3 alpha -7 beta -12 alpha -tri-hydroxycholanic, 3 alpha -7 beta -dihydroxy-12-ketocholanic, deoxycholic, dehydrocholic, iodeoxycholic, iocholic acids; M is H, Na, K, Mg, Ca; l is 1 or 2, being 2 when M = Mg or Ca.