发明名称 |
IMPROVEMENTS IN AND RELATING TO MAGNETIC RESONANCE IMAGING |
摘要 |
The invention provides a method of monitoring the vasodilatory or vasoconstrictive effects of a physiologically active substance administered to a human or non-human animal body, said method comprising the steps of: administering said substance into said body; administering into the systemic vasculature of said body a contrast enhancing amount of an intravascular paramagnetic metal containing magnetic resonance imaging contrast agent; subjecting said body to a magnetic resonance imaging procedure capable of generating from magnetic resonance signals from said body a series of temporally spaced images of at least a part of said body into which said agent passes, said procedure being a fast imaging procedure having an image acquisition time of less than five seconds; and detecting temporal variations in said signals or images whereby to monitor the vasoconstriction or vasodilation induced by said substance. |
申请公布号 |
AU7475391(A) |
申请公布日期 |
1991.10.10 |
申请号 |
AU19910074753 |
申请日期 |
1991.03.06 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
JOHN KUCHARCZYK;MICHAEL E MOSELEY;SCOTT M. ROCKLAGE |
分类号 |
A61B5/055;A61K49/00;A61K49/06;G01R33/28;G01R33/465;G01R33/561;G01R33/563 |
主分类号 |
A61B5/055 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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