| 摘要 |
(A) Cpds. of general formula (I) Including salts, and stereoisomers of I. R' = H or Me R = Me or MeCO (B) N-oxides of I (R' = Me). Antidepressants, adrenolytics, antihistamines, and local anaesthetics, with low toxicity and slight anticholinergic activity. 1-Methyl-10,11-dihydro-(3-dimethylamino-propylidene) 5H-dibenzo(a,d)cycloheptene (39.5 g), was hydrogenated at 25 deg./1 atm., over Pt2O (3 g.) in AcOH (400 ml). The mixture was filtered, evapd. and the residue distilled, giving the 3-dimethylaminopropyl deriv., b.p.140 deg./0.01 mm. (Hydrochloride m.p.181-3 deg., from Et2O-EtOH). |
