发明名称 |
Synthesis of dioxabicyclo(3.2.1)octanes and oxepanes. |
摘要 |
The synthesis of C-4 alkyl analogs of racemic (1RS,4SR,5RS)-4-(4,8-dimethyl-5-hydroxy-7-nonenyl)-4-methyl-3,8-dioxab icyclo[3.2 .1]octane-1-acetic acid and the corresponding (1RS,4RS,5RS)- derivative is described. The dioxabicyclo[3.2.1]octanes are useful as contragestational agents. The intermediate oxepane analogs are useful as intermediates in the preparation of the contragestational agent zoapatanol. |
申请公布号 |
EP0045631(A2) |
申请公布日期 |
1982.02.10 |
申请号 |
EP19810303491 |
申请日期 |
1981.07.30 |
申请人 |
ORTHO PHARMACEUTICAL CORPORATION |
发明人 |
HAJOS, ZOLTAN GEORGE;WACHTER, MICHAEL PAUL |
分类号 |
C07D321/04;C07C45/51;C07D303/32;C07D307/20;C07D313/04;C07D493/08;C07F7/18 |
主分类号 |
C07D321/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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