| 发明名称 |
PURINE BASE MODIFIED 2'-DEOXYRIBONUCLEOSIDES, USE IN TRIPLEX FORMING OLIGONUCLEOTIDES AND PROCESS FOR PREPARING THE SAME |
| 摘要 |
2088787 9221690 PCTABS00017 There are provided purine-base modified guanosine analogues, for example 2'-deoxy, and then ribonucleosides for incorporating into triplex-forming oligonucleotides. Also provided are triplex-forming oligonucleotides for binding into strands of DNA for treatment of disease and regulating genetic expression.
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| 申请公布号 |
CA2088787(A1) |
申请公布日期 |
1992.12.06 |
| 申请号 |
CA19922088787 |
申请日期 |
1992.06.04 |
| 申请人 |
TRIPLEX PHARMACEUTICAL CORPORATION;BAYLOR COLLEGE OF MEDICINE |
发明人 |
REVANKAR, GANAPATHI R.;HOGAN, MICHAEL E.;RAO, TAKKELLAPATI S.;SHROFF, HITESH N. |
| 分类号 |
A61K31/70;A61K31/7042;A61K31/7052;A61K31/7076;A61K31/708;A61K31/7088;A61K31/7135;A61P31/12;C07F7/08;C07H19/04;C07H19/16;C07H19/20;C07H19/23;C07H21/04;C07H23/00;C12N15/09;C12Q1/68;(IPC1-7):C12N15/11;C07H21/00 |
主分类号 |
A61K31/70 |
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