Process for the preparation of a complex which consists essentially of the subunit of ngf and a ganglioside selected from the group consisting of natural gangliosides semisynthetic analogues of said natural gangliosides and physiologically acceptable salts thereof

摘要

The present invention concerns new, stable and biologically active complex compounds between the proteins and gangliosides, namely, stable and biologically active complexes between the beta subunit of Nerve Growth Factor ( beta NGF) and natural gangliosides or their semisynthetic analogues such as carboxy esters and amides; as well as pharmaceutical compositions containing such complexes, their therapeutic uses and a process for their manufacture.