N-(2-hydroxyphenyl)-(thio) ureas - with antiviral activity

摘要

Cpds. of formula (I): (where R1 is Me, Et, allyl, Pr, Bu or benzyl; R2 is Me, Pr, Bu, benzyl or cyclohexyl; R3 is S or O; X is H, Cl or a sulphonamido gp.; Y is H or Br) have antiviral activity against Picorna viruses. Cpds. (I) are pref. prepd. by reacting a cpd. (II): (II) with R2NH2.