发明名称 |
SUBSTITUTED 6-PHENYLDIHYDRO-3(2H)-PYRIDAZINONES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS |
摘要 |
The present invention relates to novel 6phenyldihydro 3-(2H)-pyridazinones corresponding to the formula (I) in which R1 denotes a nitro or a cyano group, R2 denotes a hydrogen atom or a methyl group and R3 stands for an ethoxycarbonyl or an acetyl group, and the physiologically acceptable salts thereof. These compounds are readily prepared in a form suitable for oral administration and are distinguished by a high positive inotropic action and have only a slight effect on blood pressure and cardiac frequency. A process for their preparation and pharmaceutical preparations containing these compounds are also described. |
申请公布号 |
CA1316535(C) |
申请公布日期 |
1993.04.20 |
申请号 |
CA19880586764 |
申请日期 |
1988.12.22 |
申请人 |
HEUMANN PHARMA GMBH & CO |
发明人 |
HERTER, ROLF;MORSDORF, PETER;PFAHLERT, VOLKER;ENGLER, HEIDRUN;SCHICKANEDER, HELMUT;AHRENS, KURT H. |
分类号 |
A61K31/50;A61K31/505;A61P9/04;A61P9/12;C07D237/04;C07D401/10;C07D403/12;C07D417/12 |
主分类号 |
A61K31/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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