| 摘要 |
A polynucleotide probe capable of hybridizing to human genomic DNA between the TaqI sites immediately 5' and 3' of the polymorphic leader TaqI site of the human Apo(a) gene, said human genomic DNA being detectable by PCR amplification of the Apo(a) gene using the 5' and 3' primers: <IMAGE> or a polynucleotide probe capable of hybridizing to human genomic DNA between the TaqI sites immediately 5' and 3' of the polymorphic kringle TaqI site of the human Apo(a) gene, said human genomic DNA being detectable by PCR amplification of the Apo(a) gene using the 5' and 3' primers: <IMAGE> The probes can be used for family studies or population studies to ascertain alleles associated with an increased risk of heart disease. <IMAGE> |
