发明名称 |
1H-1,8-NAPHTHYRIDIN-2-ONES AS ANTI PROLIFERATIVE COMPOUNDS |
摘要 |
The present invention relates to novel antiproliferative1H-1, 8-naphthyridin-2-ones of the general formula (I) or pharmaceutically acceptable salts thereof: In which the variable groups are as defined herein, and their preparation and use in therapeutic treatment of disorders related to inhibition of tyrosine kinases in warm blooded animals. The compounds can overcome imatinib induced drug resistance. |
申请公布号 |
PH12016502432(A1) |
申请公布日期 |
2017.03.06 |
申请号 |
PH12016502432 |
申请日期 |
2016.12.06 |
申请人 |
NATCO PHARMA LIMITED |
发明人 |
KOMPELLA, AMALA;GAMPA, VENUGOPALA KRISHNA;GANGANAMONI, SRINIVASULU;SIRIGIREDDY, BALAKRISHNA REDDY;ADIBHATLA, KALI SATYA BHUJANGA RAO;NANNAPANENI, VENKAIAH CHOWDARY |
分类号 |
A61K31/4375;A61P35/02;C07D471/04 |
主分类号 |
A61K31/4375 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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