摘要 |
The present invention provides a process for the production of a pharmaceutical composition comprising a ß2-adrenerg?c agonist or a glucocorticosteroid, comprising the steps of (?) mixing a coarse excipient and a microfine excipient and sieving the resulting mixture, (??) mixing a ß2-adrenerg?c agonist or glucocorticosteroid with a microfine excipient and sieving the resulting mixture, (MI) adding the product of step (??) to a portion of the mixture obtained in step (?), and (?v) blending and/or sieving the product obtained in step (in) The process of the invention may further comprise the step of diluting the product of step (?v) with the excipient obtained according to step (?) and mixing and/or sieving to produce a final blend. |