发明名称 |
Indole derivatives and pharmaceutical compositions comprising the same. |
摘要 |
The present invention relates to indole derivatives represented by the general formula: <CHEM> wherein R represents an ethyl group or a 2,2,2-trifluoroethyl group; Y represents a hydroxy group or a pivaloyloxy group; and the carbon atom marked with (R) represents a carbon atom in (R) configuration, and pharmaceutically acceptable salts thereof, which have potent and prolonged reducing effects on intraocular pressure and are useful as agents for lowering intraocular pressure. |
申请公布号 |
ZA9901590(B) |
申请公布日期 |
1999.08.27 |
申请号 |
ZA19990001590 |
申请日期 |
1999.02.26 |
申请人 |
KISSEI PHARMACEUTICALS CO., LTD. |
发明人 |
MAKIO KITAZAWA;TOSHIAKI YAMAGUCHI;HIROSHI MIYATA;YUKIYOSHI AJISAWA |
分类号 |
A61K31/40;A61P27/06;C07D209/08 |
主分类号 |
A61K31/40 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|