发明名称 Indole derivatives and pharmaceutical compositions comprising the same.
摘要 The present invention relates to indole derivatives represented by the general formula: <CHEM> wherein R represents an ethyl group or a 2,2,2-trifluoroethyl group; Y represents a hydroxy group or a pivaloyloxy group; and the carbon atom marked with (R) represents a carbon atom in (R) configuration, and pharmaceutically acceptable salts thereof, which have potent and prolonged reducing effects on intraocular pressure and are useful as agents for lowering intraocular pressure.
申请公布号 ZA9901590(B) 申请公布日期 1999.08.27
申请号 ZA19990001590 申请日期 1999.02.26
申请人 KISSEI PHARMACEUTICALS CO., LTD. 发明人 MAKIO KITAZAWA;TOSHIAKI YAMAGUCHI;HIROSHI MIYATA;YUKIYOSHI AJISAWA
分类号 A61K31/40;A61P27/06;C07D209/08 主分类号 A61K31/40
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