| 发明名称 |
5.7-DIAMINOPYRAZOLO-4,3-DIPYRIMIDINES USEFUL FOR TREATMENT OF HYPERTENSION |
| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a pharmaceutical composition containing PDE-5 inhibitor useful for treatment of hypertension and the other diseases. <P>SOLUTION: The pharmaceutical composition comprises a compound represented by formula (I) (wherein R<SP>1</SP>is a cyclic group which may be substituted; R<SP>2</SP>is 1-2C alkyl or the like; R<SP>3</SP>and R<SP>4</SP>are each 1-8C alkyl or the like or -NR<SP>3</SP>R<SP>4</SP>forms a cyclic group; R<SP>5</SP>is a 1-6C alkyl or the like which may be substituted; R<SP>6</SP>is a 1-6C alkyl or the like which may be substituted by a cyclic group). <P>COPYRIGHT: (C)2007,JPO&INPIT</p> |
| 申请公布号 |
JP2007217419(A) |
申请公布日期 |
2007.08.30 |
| 申请号 |
JP20070067736 |
申请日期 |
2007.03.16 |
| 申请人 |
PFIZER INC |
发明人 |
BELL ANDREW SIMON;BROWN DAVID GRAHAM;FOX DAVID NATHAN ABRAHAM;MARSH IAN ROGER;MORRELL ANDREW IAN;PALMER MICHAEL JOHN;WINSLOW CAROL ANN |
| 分类号 |
A61K31/519;A61K31/5377;A61K31/551;A61K45/00;A61P1/00;A61P1/06;A61P1/12;A61P3/04;A61P3/10;A61P9/04;A61P9/08;A61P9/10;A61P9/12;A61P9/14;A61P11/00;A61P11/02;A61P11/06;A61P11/08;A61P13/06;A61P13/08;A61P13/10;A61P13/12;A61P15/00;A61P15/08;A61P15/10;A61P17/02;A61P17/06;A61P17/14;A61P25/00;A61P25/02;A61P25/04;A61P25/28;A61P29/00;A61P35/00;A61P37/08;A61P43/00;C07D487/04;C07D519/00 |
主分类号 |
A61K31/519 |
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