发明名称 |
7-MONOCHLOROACETAMIDO-3-DESACETOXYCEPHALOSPORANIC ACID DERIVATIVES, THEIR PREPARATION AND USE |
摘要 |
1454588 7-Chloroacetamido-3-desacetoxycephalosporanic acid derivatives RHONEPOULENC SA 5 Sept 1974 [6 Sept 1973] 38882/74 Heading C2C The invention comprises compounds of the formula wherein R is an ester radical, e.g. C 1 -C 4 alkyl or benzyl which may be substituted by C 1 -C 4 alkoxy. They may be obtained by (a) heating a compound of the formula in an anhydrous acid medium, or (b) treating a compound of the formula with Zn in acetic acid. 7 - Amino - 3 - desacetoxy - cephalosporanic acid is obtained by hydrolysis or hydrogenolysis of a compound of Formula I to give a compound of the formula and treating this compound with thiourea in aqueous solution. |
申请公布号 |
ZA7405657(B) |
申请公布日期 |
1975.10.29 |
申请号 |
ZA19740005657 |
申请日期 |
1974.09.05 |
申请人 |
RHONE-POULENC SA |
发明人 |
LE ROY P;MESSER M;BOUCHAUDON J |
分类号 |
C07D501/04;A61K31/545;C07D499/00;C07D501/10;C07D501/18;C07D501/22 |
主分类号 |
C07D501/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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