摘要 |
<p>Basic substd. phenylacetonitriles of formula: (I) where A, B, C = H, halogen, benzyloxy, lower alkyl or alkoxy, or 2 neighbouring gps. may form methylenedioxy; Y = 2-8C straight or branched alkyl, 2-4C being in main chain; Z = 1-8C straight or branched alkyl, 1-3C being in main chain; R = lower aliphatic gp; R1 = lower alkyl or: n = 0 or 1; at least one of A, B, C, Y, Z or R1 being other than in Belgian 615,861 and 641,269; and acid addn. salts of I. Coronary dilators with reduced toxicity.</p> |