发明名称 |
1,25-DIHYDROXY-16,22,23-TRISDEHYDRO-CHOLECALCIFEROL DERIVATIVES |
摘要 |
The invention relates to a compound of the formula SEE FORMULA I wherein R is hydroxy and R1 is H2 or CH2, or R is hydrogen or fluoro and RI is CH2. Compounds of formula I are useful as agents for the treatment of hyperproliferative skin diseases, such as psoriasis, neoplastic diseases, such as leukemia, and sebaceous gland diseases, such as acne and sebhorreic dermatitis.
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申请公布号 |
CA2199893(C) |
申请公布日期 |
2008.02.05 |
申请号 |
CA19972199893 |
申请日期 |
1997.03.13 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
HENNESSY, BERNARD MICHAEL;IACOBELLI, JEROME ANTHONY;USKOKOVIC, MILAN RADOJE |
分类号 |
A61K31/59;C07C401/00;A61P17/00;A61P35/00;A61P35/02;C07F7/18 |
主分类号 |
A61K31/59 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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