发明名称 |
S-nitrosoprotein preparation and production method therefor |
摘要 |
A protein is efficiently nitrosylated with nitrogen monoxide by merely mixing S-nitrosoglutathione as a nitrogen monoxide donor with a protein solution containing a stabilizing agent comprising at least one compound or a combination of plural compounds selected from an N-acetylamino acid, a fatty acid, and a fatty acid salt. The method that enables efficient NO addition to a cysteine residue in un-nitrosylated protein without changing the structure of protein and hence provides NO to a living organism.
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申请公布号 |
US2008051320(A1) |
申请公布日期 |
2008.02.28 |
申请号 |
US20070890542 |
申请日期 |
2007.08.07 |
申请人 |
ISHIMA YU;AKAIKE TAKAAKI;OTAGIRI MASAKI |
发明人 |
ISHIMA YU;AKAIKE TAKAAKI;OTAGIRI MASAKI |
分类号 |
A61K38/00;A61P43/00;C07K1/00;C07K14/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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