| 摘要 |
Disclosed herein are water-soluble octacarboxy substituted tetra(2,3pyrazino)porphyrazines of the following formula: (I) wherein M is HH, Cu, VO, Co, Ni or Zn; and R is C2H5, n-C4H9, n-C6H13, n-C8H17 or ONa. The present invention discloses photoinactivators and more particularly a novel class of water soluble azaphathalocyanines (AzaPc's), functionalized on the macrocyle with carboxy substituents to yield octacarboxy substituted tetra(2,3pyrazino)porphyrazines (TTPA's). The invention also relates to processes for their preparation and the use thereof for the photodynamic therapy of cancer and the inactivation of viruses or bacteria in stored blood products.
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