发明名称 Pharmaceutical compounds
摘要 Pharmaceutical compounds of the formula <IMAGE>xyl, halo, C1-4 alkyl, C1-4 alkoxy, acyloxy, -O-glucoside, optionally substituted phenyl or optionally substituted phenyl-C1-4 alkoxy; R3 is tetrazolyl, or and R4 and R5 are each hydrogen, hydroxy, acyloxy, nitro, C1-4 alkyl, C1-4 alkoxy, halo, optionally substituted phenyl, -SO3H or -NR'R'' where R' and R'' are each hydrogen or C1-4 alkyl; provided that when R3 is -CR'R''.CHR'''CO2H or tetrazolyl, R1 and R2 are each hydroxyl, halo, C1-4 alkyl, C1-4 alkoxy, acyloxy, -O-glucoside, optionally substituted phenyl or optionally substituted phenyl C1-4 alkoxy; and or a pharmaceutically acceptable salt or ester thereof.
申请公布号 US5480873(A) 申请公布日期 1996.01.02
申请号 US19930023220 申请日期 1993.02.25
申请人 LILLY INDUSTRIES LIMITED 发明人 BRUNAVS, MICHAEL;DELL, COLIN P.;DOBSON, DAVID R.;GALLAGHER, PETER T.;HICKS, TERENCE A.;OWTON, WILLIAM M.;SMITH, COLIN W.
分类号 C07D235/12;A61K31/015;A61K31/12;A61K31/165;A61K31/18;A61K31/19;A61K31/275;A61K31/41;A61K31/415;A61K31/4184;A61K31/4245;A61K31/70;A61P3/00;A61P19/10;A61P29/00;A61P35/00;A61P43/00;C07C50/18;C07C59/86;C07C65/36;C07C66/02;C07C225/36;C07C229/36;C07C233/51;C07C235/84;C07C235/88;C07C251/48;C07C255/56;C07C259/10;C07C271/42;C07C271/58;C07C307/02;C07C311/08;C07C311/21;C07C323/62;C07D235/18;C07D257/04;C07D271/10;C07F9/38;C07F9/40;C07F9/6574;(IPC1-7):C07C50/18;C07C50/20 主分类号 C07D235/12
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