摘要 |
Pharmaceutical compounds of the formula <IMAGE>xyl, halo, C1-4 alkyl, C1-4 alkoxy, acyloxy, -O-glucoside, optionally substituted phenyl or optionally substituted phenyl-C1-4 alkoxy; R3 is tetrazolyl, or and R4 and R5 are each hydrogen, hydroxy, acyloxy, nitro, C1-4 alkyl, C1-4 alkoxy, halo, optionally substituted phenyl, -SO3H or -NR'R'' where R' and R'' are each hydrogen or C1-4 alkyl; provided that when R3 is -CR'R''.CHR'''CO2H or tetrazolyl, R1 and R2 are each hydroxyl, halo, C1-4 alkyl, C1-4 alkoxy, acyloxy, -O-glucoside, optionally substituted phenyl or optionally substituted phenyl C1-4 alkoxy; and or a pharmaceutically acceptable salt or ester thereof.
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申请人 |
LILLY INDUSTRIES LIMITED |
发明人 |
BRUNAVS, MICHAEL;DELL, COLIN P.;DOBSON, DAVID R.;GALLAGHER, PETER T.;HICKS, TERENCE A.;OWTON, WILLIAM M.;SMITH, COLIN W. |