Process for the preparation of 6-hydroxymethyl-2-( beta -aminoethylthio)-1-carbadethiapen-2-em-3-carboxylic acid

摘要

Disclosed is a process for preparing the antibiotic 6-hydroxymethyl-2-( beta -aminoethylthio)-1-carbadethiapen-2-em-3-carboxylic acid (I) <IMAGE> and its pharmaceutically acceptable salt and ester derivatives. An intermediate for the production of these compounds are compounds of the formula <IMAGE> wherein R5 and R are readily removable protecting groups.