| 发明名称 |
Process for the synthesis of ergoline derivatives |
| 摘要 |
The invention provides a process for the preparation of ergoline derivatives of the formula I <IMAGE> I the process comprising reacting an ergoline amide of the formula II with an isocyanate of formula III <IMAGE> in presence of a metal catalyst and of a phosphorus compound. The compounds of the formula I are useful antiprolactinic and antiparkinson agents. |
| 申请公布号 |
ZA9301720(B) |
申请公布日期 |
1993.11.01 |
| 申请号 |
ZA19930001720 |
申请日期 |
1993.03.10 |
| 申请人 |
FARMITALIA CARLO ERBA S.R.L. |
发明人 |
IIARIA CANDIANI;WALTER CABRI;ANGELO BEDESCHI;FRANCO ZARINI |
| 分类号 |
A61K31/48;A61P5/08;A61P25/16;C07D457/06 |
主分类号 |
A61K31/48 |
| 代理机构 |
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