ORAL PEPTIDE PHARMACEUTICAL PRODUCTS

摘要

Bioavailability of peptide active agents to be administered orally is enhanc ed by a pharmaceutical composition providing targeted release of the peptide to the intestine by virtue of an acid-resistant protective vehicle which transports components of the invention through the stomach. The composition includes an absorption enhancer and a sufficien t amount of a pH-lowering agent to lower local intestinal pH. All components are released together into the intestine with the peptid e.