发明名称 |
SUBSTITUTED SULFONIMIDAMIDES, PROCESSES FOR THEIR PREPARATION, THEIR USE AS A MEDICAMENT OR DIAGNOSTIC, AND MEDICAMENT COMPRISING THEM |
摘要 |
Substituted sulfonimidamides, processes for their preparation, their use as a medicament or diagnostic, and medicament comprising them Sulfonimidamides of the formula I in which at least one of the three substituents R(1), R(2) and R(3) is a benzoylguanidine, and in which the other substituents have the meanings indicated in the claims, are outstandingly suitable as medicaments having action on the cardiovascular system; that is as antiarrhythmic pharmaceuticals having a cardioprotective component as well as for treating ischemically induced damage; also in operative interventions, such as organ transplantation.
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申请公布号 |
CA2189221(A1) |
申请公布日期 |
1997.05.04 |
申请号 |
CA19962189221 |
申请日期 |
1996.10.30 |
申请人 |
HOECHST AKTIENGESELLSCHAFT |
发明人 |
KLEEMANN, HEINZ-WERNER;BRENDEL, JOACHIM;SCHWARK, JAN-ROBERT;WEICHERT, ANDREAS;LANG, HANS JOCHEN;ALBUS, UDO;SCHOLZ, WOLFGANG |
分类号 |
A61K31/165;A61K31/18;A61P1/16;A61P3/08;A61P9/04;A61P9/08;A61P9/10;A61P11/00;A61P13/02;A61P15/00;A61P35/00;A61P41/00;A61P43/00;C07C279/18;C07C313/02;C07C313/06;C07C381/10;(IPC1-7):C07C381/10;C07D295/155;C07D333/30;A61K31/33;C07D207/34;C07D307/56;C07D213/60 |
主分类号 |
A61K31/165 |
代理机构 |
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地址 |
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