发明名称 Heterocyclic compounds
摘要 Compounds of the formula (II): <CHEM> or acid addition salts thereof, wherein R<1> is hydrogen, C1-6 alkyl or C1-4 alkyl substituted by halo or C1-4 alkoxy, R<2> is C1-4 alkyl or C1-4 alkyl substituted b halo or C1-4 alkoxy, R<3> is C1-4 alkyl or C1-4 alkyl substituted by halo or C1-4 alkoxy or <CHEM> forms a C5-7 cycloalkyl or cycloalkenyl group and R<4> is hydrogen or C1-4 alkyl are described as useful medicaments in the treatment of cancer. Pharmaceutical compositions containing the compounds and their manufacture are also disclosed.
申请公布号 ZA9208661(B) 申请公布日期 1994.05.11
申请号 ZA19920008661 申请日期 1992.11.10
申请人 THE WELLCOME FOUNDATION LIMITED. 发明人 LEE FREDERICK KUYPER;MICHAEL LEE JONES;DAVID PATRICK BACCANARI
分类号 C07D487/04 主分类号 C07D487/04
代理机构 代理人
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