A human BMP-10 polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for stimulating de novo bone synthesis. Diagnostic assays for identifying mutations in nucleic acid sequence encoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention for detecting diseases, for example cancer, are also disclosed.
申请公布号
WO9639431(A1)
申请公布日期
1996.12.12
申请号
WO1995US07915
申请日期
1995.06.06
申请人
HUMAN GENOME SCIENCES, INC.;HE, WEI, WU;COLEMAN, TIMOTHY, A.;HASTINGS, GREGG, A.;ROSEN, CRAIG, A.
发明人
HE, WEI, WU;COLEMAN, TIMOTHY, A.;HASTINGS, GREGG, A.;ROSEN, CRAIG, A.
