| 摘要 |
Pharmaceutical composition comprising at least one compound having a structural formula selected of the isomers IA or IB: (IA) (IB) wherein R1 = H or alkyl or F or Cl or Br or I; R2, R3, R4 = are independently from each other H, methyl, ethyl or (R2 and R3) or (R3 and R4) are forming a methylene or ethylene bridging structure between the oxygen atoms linked to R2, R3 or R4; R5 = H or methyl; H, methyl or fluorinated or partially fluorinated methyl or ethyl; X = O or S; XR6 may also be F; Y = (CH2)m R7 n (CH2)q with R7 = O, NH or NR8, R8 = alkyl, acyl or aryl and the proviso that (independently from each other) m, n, q = 0, 1, 2 and ∑(m+n+q) = 1, 2 or 3; Z = single or double bonded organic residue comprising methyl or methylene, =O, -OH, NHR, OR, NH2, NH-acyl, N3, triazole or substituted triazole, CH2-triazole, CH2-SH, CH2SR, CH2NH2, CH2NHR, CH2N3, CH2OR, CH2OC(O)OR (carbonate), CH2OC(O)NHR, CH2NHC(O)OR (carbamate), CH2NHC(O)NHR (urea), CH2NHC(S)NHR (thiourea) with R = alkyl, aryl, acyl, C(O)-, CH2-triazole. |
