METHODS AND COMPOSITIONS FOR MODULATING BK CHANNEL ACTIVITY AND VASODILATION
摘要
Methods and compositions are provided for modulating myocyte BK channel activity and for screening for modulators of BK channel activity. The methods and compositions are useful in the treatment of disorders where increasing myocyte BK channel activity can attenuate, revert or prevent the disorder. For example, the methods and compositions are useful for treating disorders ameliorated by increasing vasodilation and blood flow in a subject, in particular, increasing cerebral blood flow.
申请公布号
WO2008085492(A3)
申请公布日期
2008.09.12
申请号
WO2007US26364
申请日期
2007.12.27
申请人
UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION;DOPICO, ALEJANDRO, M.;BUKIYA, ANNA, NODAROVNA;LIU, JIANXI