| 摘要 |
Linear peptides of the formula I X-A-Cys(R1)-B-Z I, in which A, B, R1, X and Z are as defined, are highly active inhibitors of the binding of the blood platelet integrin GP IIbIIIa (aIIb beta 3) to natural ligands and are suitable, inter alia, for the prophylaxis and for the treatment of circulatory disorders, thrombosis, myocardial infarction, coronary heart disease, arteriosclerosis, atherosclerosis, tumors and osteolytic diseases, and have a supporting effect in wound healing processes.
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