发明名称 |
DETECTION OF HUMAN CANCER CELLS WITH ANTIBODIES TO HUMAN CANCER NUCLEOLAR ANTEGEN(S) |
摘要 |
<p>Specific common nucleolar antigen(s) are found in a broad range of human malignant tumor specimens and have been isolated, extracted and purified. Antibodies and antisera specific to these nucleolar antigen(s) are harvested from non-human hosts and used for detection of human cancer cells. Disclosed are (1) methods for isolating the nucleolar antigen(s), obtaining them in substantially purified form, producing the specific antibodies, obtaining them in substantially purified form, and using the antisera and antibodies induced by the nucleolar antigen(s) in diagnostic procedures for detecting human cancer cells, and (2) diagnostic kits comprising specific antibodies and antisera.</p> |
申请公布号 |
CA1172165(A) |
申请公布日期 |
1984.08.07 |
申请号 |
CA19830424445 |
申请日期 |
1983.03.24 |
申请人 |
BAYLOR COLLEGE OF MEDICINE |
发明人 |
BUSCH, HARRIS;BUSCH, ROSE K.;GYORKEY, FERENC;GYORKEY, PHYLLIS;DAVIS, FRANCES M.;SMETANA, KAREL |
分类号 |
A61K39/00;(IPC1-7):A61K39/00;G01N33/54 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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