7-aminocephalosporanic acid derivs antibacterial

摘要

(A) 7-Aminocephalosporanic acid derivs. (I) R1 = opt. hydrogenated imidazolium or imidazolyl, bound with an N-atom to the acetylamino R2 = a free- or carboxylic acid-esterified hydroxy group in which the ester-O-atoms are opt. replaced by -S; opt. N-substd. carbamoyloxy in which the -O-atoms are opt. replaced by -Sf or a quaternary amino group. (B) Salts of (I) including internal salts. (I) have antibacterial activity against Gram-pos. and esp. Gram-neg. bacteria such as penicillin-resistant S. aureus, E. coli, K. pneumoniae, S. typhosa and B. proteus. They may be used in the treatment of infections caused by these micro-organisms or may be used as feedstuff-additives, as food preserving- or disinfecting agents.