发明名称 Pyrimido[5,4-c] Quinoline-2, 4-Diamine Derivatives and Methods of Use Thereof
摘要 The present invention relates to pyrimido[5,4-c]quinoline-2,4-diamine derivatives, compositions comprising an effective amount of a Pyrimido[5,4-c]quinoline-2,4-diamine Derivative, methods for treating or preventing a proliferative disorder, comprising administering to a subject in need thereof an effective amount of an Pyrimido[5,4-c]quinoline-2,4-diamine Derivative, methods for modulating PDK-1 activity, comprising administering to a subject in need thereof an effective amount of a Pyrimido[5,4-c]quinoline-2,4-diamine Derivative. The invention also relates to a process for preparing a Pyrimido[5,4-c]quinoline-2,4-diamine Derivative.
申请公布号 US2008234300(A1) 申请公布日期 2008.09.25
申请号 US20080042092 申请日期 2008.03.04
申请人 WYETH 发明人 WISSNER ALLAN;VENKATESAN ARANAPAKAM M.
分类号 A61K31/519;A61P35/00;C07D471/04 主分类号 A61K31/519
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