发明名称 |
CRUSTACEAN ANTIMICROBIAL PEPTIDES, CALLED PENAIEDINES |
摘要 |
The invention concerns antimicrobial peptides obtained from penaeid prawns having the following characteristics: the molecular mass of about 5 to 7 kDa; the pHi not less than 9; the N-terminal portion comprises a region (A) of about 15 to 25 amino acids rich in proline; and the C-terminal portion comprises a region (B) of about 20 to 30 amino acids, containing 6 cysteine residues forming three intramolecular disulphide bonds. The invention also concerns the nucleic acid sequences coding for said peptides, and enabling their production by genetic engineering. |
申请公布号 |
WO9905270(A3) |
申请公布日期 |
1999.05.27 |
申请号 |
WO1998FR01583 |
申请日期 |
1998.07.20 |
申请人 |
INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER (IFREMER);CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);DESTOUMIEUX, DELPHINE;BACHERE, EVELYNE;BULET, PHILIPPE |
发明人 |
DESTOUMIEUX, DELPHINE;BACHERE, EVELYNE;BULET, PHILIPPE |
分类号 |
A61K38/00;A61P31/00;C07K14/435;C12N15/12 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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