发明名称 NEW CRYSTAL FORM OF NERATINIB MALEATE AND PREPARATION METHOD THEREFOR
摘要 The present invention relates to a new crystal form of neratinib maleate and a preparation method therefor. A new crystal form of the maleate of a compound as represented by formula (I) of the present invention has advantageous properties of high solubility, good stability, technological availability and tractability, and the preparation method is simple and requires low costs, which is of important value for the optimization and development of the drug in the future.
申请公布号 WO2016110270(A1) 申请公布日期 2016.07.14
申请号 WO2016CN70472 申请日期 2016.01.08
申请人 CRYSTAL PHARMATECH CO., LTD 发明人 CHEN, MINHUA;ZHANG, YANFENG;DIAO, XIAOJUAN;ZHANG, XIAOYU
分类号 C07D401/12;A61K31/4709;A61P35/00 主分类号 C07D401/12
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