发明名称 |
HIGH THROUGHPUT SCREEN |
摘要 |
The present invention relates to a structure comprising a biological membrane and a porous or perforated substrate, a biological membrane, a substrate, a high throughput screen, methods for production of the structure membrane and substrate, and a method for screening a large number of test compounds in a short period. More particularly it relates to a structure comprising a biological membrane adhered to a porous or perforated substrate, a biological membrane capable of adhering with high resistance seals to a substrate such as perforated glass and the ability to form sheets having predominantly an ion channel or transporter of interest, a high throughput screen for determining the effect of test compounds on ion channel or transporter activity, methods for manufacture of the structure, membrane and substrate, and a method for monitoring ion channel or transporter activity in a membrane. |
申请公布号 |
WO9966329(A1) |
申请公布日期 |
1999.12.23 |
申请号 |
WO1999GB01871 |
申请日期 |
1999.06.14 |
申请人 |
CENES LIMITED;OWEN, DAVID, GERAINT;BYRNE, NICHOLAS, GERARD |
发明人 |
OWEN, DAVID, GERAINT;BYRNE, NICHOLAS, GERARD |
分类号 |
G01N33/50;G01N33/543;G01N33/68;G01N37/00 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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