| 摘要 |
The present invention relates to a multiple-unit dose composition comprising furosemide as pharmaceutically active compound, whereby the composition gives a release of furosemide in accordance with Dissotest in a buffer having pH 1.5 of at most 4% during hour 1, a release in a buffer having pH 5.5 of at most 7.5% during a consequtive hour (hour 2), a release of furosemide in a buffer having pH 7.5 of at least 65% during a further consequtive hour (hour 3), and a release of furosemide in a buffer having pH 7.5 of at least 90% during a consequtive hour (hour 4). |
