| 摘要 |
NEW MATERIAL:A compound expressed by formula I (n is 1-5). EXAMPLE:N-(3-Fluorophenyl)-7-oxabicyclo[2.2.1] hept-5-ene-2,3,-dicarboximide. USE:A remedy for liver diseaes, for example, jecur adiposum, alcoholic hepatitis, toxic hepatopathy, hemostatic liver, cholestatic hepatopathy, hepatocirrhosis, etc. PREPARATION:For example, a compound expressed by formula II (example; 3-fluoroaniline, etc.) and 3,6-endooxo-1,2,3,6-tetrahydrophthalic anhydride are subjected to condensation reaction with dehydration preferably n the presence of a solvent such as acetic acid, etc., suitably at 50-150 deg.C for 30min-5hr while heating.
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