发明名称 |
Process for preparing loracarbef monohydrate |
摘要 |
The invention is directed to a crystalline anhydrate solvate of loracarbef, and also is directed to a process for preparing a crystalline monohydrate form of the compound of formula (I) <IMAGE> (I) which comprises drying a crystalline isopropanolate form of the compound of formula (I) at a temperature of from about 50 DEG C. to about 100 DEG C. to provide a crystalline anhydrate form of the compound of formula (I); and exposing the crystalline anhydrate form of the compound of formula (I) to a relative humidity of from about 90 to about 100%.
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申请公布号 |
US5580977(A) |
申请公布日期 |
1996.12.03 |
申请号 |
US19950396948 |
申请日期 |
1995.03.01 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
HENNING, WILLIAM C.;STOUT, THEODORE R. |
分类号 |
C07D471/04;C07D463/00;C07D463/22;(IPC1-7):C07D487/04 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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