| 发明名称 |
ARABINOSYLATED GLYCOPROTEINS |
| 摘要 |
The present invention relates to the field of protein production and, in particular, to methods and compositions for modulating glycosylation of proteins expressed by host cells. In particular glycoproteins are produced in presence of arabinose and or altrose, whereby N-linked glycans are afucosylated and replaced with arabinosylated N-linked glycans. |
| 申请公布号 |
WO2016144773(A1) |
申请公布日期 |
2016.09.15 |
| 申请号 |
WO2016US20931 |
申请日期 |
2016.03.04 |
| 申请人 |
ABBVIE INC. |
发明人 |
HOSSLER, Patrick;IBRAGHIMOV, Alexander;SERNA, Daniel, M.;OUTELLETTE, David, R.;CHUMSAE, Chris, M. |
| 分类号 |
C07K16/00;C07K16/24;C07K16/28;C12N5/02;C12P21/08 |
主分类号 |
C07K16/00 |
| 代理机构 |
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