| 发明名称 |
C-6 MODIFIED INDAZOLYLPYRROLOTRIAZINES |
| 摘要 |
The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby maki ng them useful as antiproliferative agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transducti on pathways operating through growth factor receptors.
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| 申请公布号 |
CA2509650(C) |
申请公布日期 |
2007.10.30 |
| 申请号 |
CA20032509650 |
申请日期 |
2003.12.12 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
VITE, GREGORY D.;KADOW, JOHN F.;MASTALERZ, HAROLD;FINK, BRIAN E.;GAVAI, ASHVINIKUMAR V. |
| 分类号 |
C07D487/04;A61K;A61K31/53;A61K31/5377;A61P13/08;A61P19/02;A61P29/00;A61P35/00;A61P37/00;C07D;C07D487/02 |
主分类号 |
C07D487/04 |
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