| 发明名称 |
PLASTER CONTAINING FENTANYL |
| 摘要 |
A process for producing an adhesive matrix for a transdermal therapeutic system comprising a cover layer, the adhesive matrix, and a removable protective layer. The process includes providing a solution comprising polybutyl titanate dissolved in heptane:ethyl alcohol, providing an acrylate copolymer consisting of units of 2-ethylhexyl acrylate, methacrylate and 2-hydroxyethyl acrylate, adding the solution to the acrylate copolymer to obtain a mixture, and adding fentanyl as an active ingredient to the mixture to obtain the adhesive matrix. |
| 申请公布号 |
US2016158161(A1) |
申请公布日期 |
2016.06.09 |
| 申请号 |
US201615045267 |
申请日期 |
2016.02.17 |
| 申请人 |
TESA LABTEC GMBH |
发明人 |
CORDES Guenter;VOLLMER Ulrike |
| 分类号 |
A61K9/70;A61K47/32;A61K47/10;A61K31/445;A61K47/24 |
主分类号 |
A61K9/70 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A process for producing an adhesive matrix for a transdermal therapeutic system comprising a cover layer, the adhesive matrix, and a removable protective layer, the process comprising:
providing a solution comprising polybutyl titanate dissolved in heptane:ethyl alcohol; providing an acrylate copolymer consisting of units of 2-ethylhexyl acrylate, methacrylate and 2-hydroxyethyl acrylate; adding the solution to the acrylate copolymer to obtain a mixture; and adding fentanyl as an active ingredient to the mixture to obtain the adhesive matrix. |
| 地址 |
Langenfeld DE |
