发明名称 |
BENZODIOXANE INHIBITORS OF LEUKOTRIENE PRODUCTION |
摘要 |
Described are compounds of formula (I)wherein Rto R, A, X and n are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene Ahydrolase (LTAH) and treating LTAH related disorder. The present invention also describes pharmaceutical compositions comprising the compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds. |
申请公布号 |
EA023876(B1) |
申请公布日期 |
2016.07.29 |
申请号 |
EA20130001019 |
申请日期 |
2012.03.13 |
申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
ABEYWARDANE ASITHA;BURKE MICHAEL, J.;KIRRANE THOMAS, MARTIN, JR.;NETHERTON MATTHEW, RUSSELL;PADYANA ANIL, KUMAR;SMITH KEENAN LANA, LOUISE;TAKAHASHI HIDENORI;TURNER MICHAEL, ROBERT;ZHANG QIANG;ZHANG QING |
分类号 |
C07D319/20;A61K31/357;A61P19/00;A61P29/00;C07D405/10;C07D405/14;C07D487/10;C07D487/12 |
主分类号 |
C07D319/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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