A novel anti-tumor and antimicrobial compound, its microbiological preparation and its use as medicament.

摘要

The present invention relates to a novel antibiotic and a microbial process of producing the same. The compound MF 730-N6, which is characterized by the following properties: melting point: 115 - 119 DEG C rotation as measured immediately after preparation of a solution of the antibiotic: [ alpha ] @@ = -28.5 DEG (C = 0.46, chloroform) solubility: soluble in methanol, ethanol, ethyl acetate and ultraviolet absorption spectrum: lambda <CHEM> = 203 nm (60), 280 nm (3) infrared absorption spectrum: distinct characteristic absorption maxima appearing at wave numbers of 3430, 2960, 1705 and 1635 cm<-><1> by the KBr tablet method, is obtained by cultivating a microorganismus of the genus Kitasatosporia capable of producing the compound MF 730-N6 on a nutrient medium and recovering said compound from the culture by usual methods of solvent extraction and/or chromatography, has both anti-tumor and anti-microbial activities and can, therefore, be used as a medicament.