发明名称 CARBOXAMIDE DERIVATIVES AS PESTICIDAL COMPOUNDS
摘要 Disclosed are compounds of formula (I) which possess pesticidal, especially nematicidal properties wherein in the structural elements have the meaning as indicated in the description.;
申请公布号 US2016221950(A1) 申请公布日期 2016.08.04
申请号 US201415022583 申请日期 2014.10.10
申请人 BAYER ANIMAL HEALTH GMBH 发明人 SCHWARZ Hans-Georg;DECOR Anne;FÜßLEIN Martin;GÖRGENS Ulrich;ILG Kerstin;WELZ Claudia;LÜMMEN Peter;KÖHLER Adeline;BÖRNGEN Kirsten
分类号 C07D213/40;C07D405/04;C07D213/38;A01N43/60;C07D401/10;A01N43/84;A01N43/40;C07D401/12 主分类号 C07D213/40
代理机构 代理人
主权项 1. A compound of formula (I) wherein B1, B2 represent C—X or N, wherein at least B1 or B2 is N, n is 0, 1, 2, 3 or 4, limited by the number of available positions in the ring to which a substituent X can be connected, each X is independently selected from the group consisting of hydrogen, halogen, nitro, cyano, hydroxy, amino, —SH, —SF5, —CHO, —OCHO, —NHCHO, —COOH, —CONH2, —CONH(OH), —OCONH2, (hydroxyimino)-C1-C6-alkyl, C1-C8-alkyl, C1-C8-halogenoalkyl having 1 to 5 halogen atoms, C2-C8-alkenyl, C2-C8-alkynyl, C1-C8-alkylamino, di-(C1-C8-alkyl)amino, C1-C8-alkoxy, C1-C8-halogenoalkoxy having 1 to 5 halogen atoms, C2-C8-alkenyloxy, C2-C8-halogenoalkenyloxy having 1 to 5 halogen atoms, C3-C8-alkynyloxy, C3-C8-halogenoalkynyloxy having 1 to 5 halogen atoms, C3-C8-cycloalkyl, C3-C8-halogenocycloalkyl having 1 to 5 halogen atoms, C1-C8-alkylcarbonyl, C1-C8-halogenoalkylcarbonyl having 1 to 5 halogen atoms, —CONH(C1-C8-alkyl), —CON(C1-C8-alkyl)2, —CONH(OC1-C8-alkyl), —CON(OC1-C8-alkyl)(C1-C8-alkyl), C1-C8-alkoxycarbonyl, C1-C8-halogenoalkoxycarbonyl having 1 to 5 halogen atoms, C1-C8-alkylcarbonyloxy, C1-C8-halogenoalkylcarbonyloxy having 1 to 5 halogen atoms, C1-C8-alkylcarbonylamino, C1-C8-halogenoalkylcarbonylamino having 1 to 5 halogen atoms, —OCONH(C1-C8-alkyl), —OCON(C1-C8-alkyl)2, —OCONH(OC1-C8-alkyl), —OCO(OC1-C8-alkyl), —S—C1-C8-alkyl, —S—C1-C8-halogenoalkyl having 1 to 5 halogen atoms, —S(O)—C1-C8-alkyl, —S(O)—C1-C8-halogenoalkyl having 1 to 5 halogen atoms, —S(O)2—C1-C8-alkyl, —S(O)2—C1-C8-halogenoalkyl having 1 to 5 halogen atoms, (C1-C6-alkoxyimino)-C1-C6-alkyl, (C2-C6-alkenyloxyimino)-C1-C6-alkyl, (C3-C6-alkynyloxyimino)-C1-C6-alkyl, (benzyloxyimino)-C1-C6-alkyl, benzyloxy, —S-benzyl, benzylamino, phenoxy, —S-phenyl and phenylamino, m is 0, 1, 2, 3, 4 or 5, and each Y is independently selected from the group consisting of hydrogen, halogen, nitro, cyano, hydroxy, amino, —SH, —SF5, —CHO, —OCHO, —NHCHO, —COOH, —CONH2, —CONH(OH), —OCONH2, (hydroxyimino)-C1-C6-alkyl, C1-C8-alkyl, C1-C8-halogenoalkyl having 1 to 5 halogen atoms, C2-C8-alkenyl, C2-C8-alkynyl, C1-C8-alkylamino, di-(C1-C8-alkyl)amino, wherein both alkyl residues may form a 4- to 7-membered heterocycle incorporating the nitrogen bonded to the phenyl system of the compound, C1-C8-alkoxy, C1-C8-halogenoalkoxy having 1 to 5 halogen atoms, C2-C8-alkenyloxy, C2-C8-halogenoalkenyloxy having 1 to 5 halogen atoms, C3-C8-alkynyloxy, C3-C8-halogenoalkynyloxy having 1 to 5 halogen atoms, C3-C8-cycloalkyl, C3-C8-halogenocycloalkyl having 1 to 5 halogen atoms, C1-C8-alkylcarbonyl, C1-C8-halogenoalkylcarbonyl having 1 to 5 halogen atoms, —CONH(C1-C8-alkyl), —CON(C1-C8-alkyl)2, —CONH(OC1-C8-alkyl), —CON(OC1-C8-alkyl)(C1-C8-alkyl), C1-C8-alkoxycarbonyl, C1-C8-halogenoalkoxycarbonyl having 1 to 5 halogen atoms, C1-C8-alkylcarbonyloxy, C1-C8-halogenoalkylcarbonyloxy having 1 to 5 halogen atoms, C1-C8-alkylcarbonylamino, C1-C8-halogenoalkylcarbonylamino having 1 to 5 halogen atoms, —OCONH(C1-C8-alkyl), —OCON(C1-C8-alkyl)2, —OCONH(OC1-C8-alkyl), —OCO(OC1-C8-alkyl), —S—C1-C8-alkyl, —S—C1-C8-halogenoalkyl having 1 to 5 halogen atoms, —S(O)—C1-C8-alkyl, —S(O)—C1-C8-halogenoalkyl having 1 to 5 halogen atoms, —S(O)2—C1-C8-alkyl, —S(O)2—C1-C8-halogenoalkyl having 1 to 5 halogen atoms, —CH2—S—C1-C8-alkyl, —CH2—S(O)—C1-C8-alkyl, —CH2—S(O)2—C1-C8-alkyl, (C1-C6-alkoxyimino)-C1-C8-alkyl, (C2-C6-alkenyloxyimino)-C1-C8-alkyl, (C3-C6-alkynyloxyimino)-C1-C6-alkyl, (benzyloxyimino)-C1-C8-alkyl, benzyloxy, —S-benzyl, benzylamino, phenoxy, —S-phenyl and phenylamino, or m is 2, 3, 4 or 5, and at least two substituents Y are vicinal and, together with the carbon atoms to which they are bonded, form an annellated 5- or 6-membered carbocycle or a 5- or 6-membered heterocycle with one or two heteroatoms selected from the group consisting of oxygen and nitrogen, whereat two oxygen atoms are not directly connected, the carbocycle or heterocycle being independently substituted by 0 to 4 halogen atoms, 0 to 2 oxo-groups, 0 to 8 C1-C8-alkyl, 0 to 8 C1-C8-alkoxy or 0 to 4 C1-C8-halogenoalkyl having 1 to 5 halogen atoms, and the remaining substituents Y are independently selected from the group consisting of hydrogen, halogen, nitro, cyano, hydroxy, amino, —SH, —SF5, —CHO, —OCHO, —NHCHO, —COOH, —CONH2, —CONH(OH), —OCONH2, (hydroxyimino)-C1-C6-alkyl, C1-C8-alkyl, C1-C8-halogenoalkyl having 1 to 5 halogen atoms, C2-C8-alkenyl, C2-C8-alkynyl, C1-C8-alkylamino, di-(C1-C8-alkyl)amino, C1-C8-alkoxy, C1-C8-halogenoalkoxy having 1 to 5 halogen atoms, C2-C8-alkenyloxy, C2-C8-halogenoalkenyloxy having 1 to 5 halogen atoms, C3-C8-alkynyloxy, C3-C8-halogenoalkynyloxy having 1 to 5 halogen atoms, C3-C8-cycloalkyl, C3-C8-halogenocycloalkyl having 1 to 5 halogen atoms, C1-C8-alkylcarbonyl, C1-C8-halogenoalkylcarbonyl having 1 to 5 halogen atoms, —CONH(C1-C8-alkyl), —CON(C1-C8-alkyl)2, —CONH(OC1-C8-alkyl), —CON(OC1-C8-alkyl) (C1-C8-alkyl), C1-C8-alkoxycarbonyl, C1-C8-halogenoalkoxycarbonyl having 1 to 5 halogen atoms, C1-C8-alkylcarbonyloxy, C1-C8-halogenoalkylcarbonyloxy having 1 to 5 halogen atoms, C1-C8-alkylcarbonylamino, C1-C8-halogenoalkylcarbonylamino having 1 to 5 halogen atoms, —OCONH(C1-C8-alkyl), —OCON(C1-C8-alkyl)2, —OCONH(OC1-C8-alkyl), —OCO(OC1-C8-alkyl), —S—C1-C8-alkyl, —S—C1-C8-halogenoalkyl having 1 to 5 halogen atoms, —S(O)—C1-C8-alkyl, —S(O)—C1-C8-halogenoalkyl having 1 to 5 halogen atoms, —S(O)2—C1-C8-alkyl, —S(O)2—C1-C8-halogenoalkyl having 1 to 5 halogen atoms, —CH2—S—C1-C8-alkyl, —CH2—S(O)—C1-C8-alkyl, —CH2—S(O)2—C1-C8-alkyl, (C1-C6-alkoxyimino)-C1-C6-alkyl, (C2-C6-alkenyloxyimino)-C1-C6-alkyl, (C3-C6-alkynyloxyimino)-C1-C6-alkyl, (benzyloxyimino)-C1-C6-alkyl, benzyloxy, —S-benzyl, benzylamino, phenoxy, —S-phenyl and phenylamino, R1, R2, R3 and R4 are the same or different and are selected from the group consisting of hydrogen, halogen, cyano, hydroxy, amino, —SH, —CHO, —OCHO, —NHCHO, —COOH, —CONH2, —CONH(OH), —OCONH2, a (hydroxyimino)-C1-C6-alkyl group, C1-C6-alkyl, C2-C6-alkenyl, C2-C6-alkynyl, C1-C6-alkylamino, di-(C1-C6-alkyl)amino, C1-C6-alkoxy, hydroxy-C1-C4-alkyl, C1-C4-alkoxy-C1-C3-alkyl, C1-C6-halogenoalkyl having 1 to 5 halogen atoms, C1-C6-halogenoalkoxy having 1 to 5 halogen atoms, C2-C6-alkenyloxy, C2-C6-halogenoalkenyloxy having 1 to 5 halogen atoms, C3-C6-alkynyloxy, C3-C6-halogenoalkynyloxy having 1 to 5 halogen atoms, C3-C6-cycloalkyl, C3-C6-halogenocycloalkyl having 1 to 5 halogen atoms, C3-C6-cycloalkyl-C1-C6-alkyl, C3-C6-halogenocycloalkyl-C1-C8-alkyl having 1 to 5 halogen atoms, C1-C6-alkylcarbonyl, C1-C6-halogenoalkylcarbonyl having 1 to 5 halogen atoms, —CONH(C1-C6-alkyl), —CON(C1-C6-alkyl)2, —CONH(OC1-C6-alkyl), —CON(OC1-C6-alkyl)(C1-C6-alkyl), C1-C6-alkoxycarbonyl, a C1-C6-halogenoalkoxycarbonyl having 1 to 5 halogen atoms, —OC(O)—C1-C6-alkyl, —OC(O)—C1-C6-halogenoalkyl having 1 to 5 halogen atoms, —NHC(O)—C1-C6-alkyl, —NHC(O)—C1-C6-halogenoalkyl having 1 to 5 halogen atoms, —OCONH(C1-C6-alkyl), —OCON(C1-C6-alkyl)2, —OCONH(OC1-C6-alkyl), OCO(OC1-C6-alkyl), —S—C1-C6-alkyl, —S—C1-C6-halogenoalkyl having 1 to 5 halogen atoms, —S(O)—C1-C6-alkyl, —S(O)—C1-C6-halogenoalkyl having 1 to 5 halogen atoms, —S(O)2—C1-C6-alkyl, —S(O)2—C1-C6-halogenoalkyl having 1 to 5 halogen atoms, benzyl, benzyloxy, —S-benzyl, —S(O)-benzyl, —S(O)2-benzyl, benzylamino, phenoxy, —S-phenyl, —S(O)-phenyl, —S(O)2-phenyl, phenylamino, phenylcarbonylamino and phenyl, with the provisio that R1 is fluorine and/or R2 is fluorine, R5 is selected from the group consisting of hydrogen, cyano, —CHO, —OH, C1-C6-alkyl, C1-C6-halogenoalkyl having 1 to 5 halogen atoms, C1-C6-alkoxy, C1-C6-halogenoalkoxy having 1 to 5 halogen atoms, C3-C7-cycloalkyl, C3-C7-halogenocycloalkyl having 1 to 5 halogen atoms, C3-C7-cycloalkyl-C1-C6-alkyl, —CONH(C1-C6-alkyl), C2-C6-alkenyl, C2-C6-alkynyl, C1-C6-alkoxy-C1-C6-alkyl, C3-C7-cycloalkyl-C1-C6-alkyl, cyano-C1-C6-alkyl, amino-C1-C6-alkyl, C1-C6-alkylamino-C1-C6-alkyl, di-(C1-C6-alkyl)amino-C1-C6-alkyl, C1-C6-alkylcarbonyl, C1-C6-halogenoalkylcarbonyl having 1 to 5 halogen atoms, C1-C6-alkoxycarbonyl, C1-C6-benzyloxycarbonyl, C1-C6-alkoxy-C1-C6-alkylcarbonyl, —S—C1-C6-alkyl, —S—C1-C6-halogenoalkyl having 1 to 5 halogen atoms, —S(O)2—C1-C6-alkyl, and S(O)2—C1-C6-halogenoalkyl having 1 to 5 halogen atoms, A represents a phenyl group of the formula (A1)  wherein o is 0, 1, 2, 3, 4 or 5, and each R is independently selected from the group consisting of halogen, nitro, —OH, NH2, SH, SF5, CHO, OCHO, NHCHO, COOH, cyano, C1-C8-alkyl, C1-C8-halogenoalkyl having 1 to 9 halogen atoms, C2-C8-alkenyl, C2-C8-alkynyl, C3-C6-cycloalkyl, —S—C1-C8-alkyl, —S—C1-C8-halogenoalkyl having 1 to 5 halogen atoms, C1-C8-alkoxy, C1-C8-halogenoalkoxy having 1 to 5 halogen atoms, C1-C8-alkoxy-C2-C8-alkenyl, C1-C8-alkoxycarbonyl, C1-C8-halogenoalkoxycarbonyl having 1 to 5 halogen atoms, C1-C8-alkylcarbonyloxy, C1-C8-halogenoalkylcarbonyloxy having 1 to 5 halogen atoms, —S(O)—C1-C8-alkyl, —S(O)—C1-C8-halogenoalkyl having 1 to 5 halogen atoms, —S(O)2—C1-C8-alkyl, —S(O)2—C1-C8-halogenoalkyl having 1 to 5 halogen atoms, C1-C8-alkylsulfonamide, —NH(C1-C8-alkyl), N(C1-C8-alkyl)2, phenyl (optionally substituted by C1-C6-alkoxy) and phenoxy, or two R bonded to adjacent carbon atoms together represent —O(CH2)pO—, wherein p represents 1 or 2, or A represents a heterocycle of the formula (Het-1) in which R6 and R7 may be the same or different and are selected from the group consisting of hydrogen, halogen, amino, nitro, C1-C4-alkyl and C1-C4-halogenoalkyl having 1 to 5 halogen atoms, and R8 is selected from the group consisting of hydrogen, halogen, nitro, C1-C4-alkyl and C1-C4-halogenoalkyl having 1 to 5 halogen atoms, or A represents a heterocycle of the formula (Het-2) in which R9 is selected from the group consisting of hydrogen, halogen, C1-C4-alkyl and C1-C4-halogenoalkyl having 1 to 5 halogen atoms, and R10 and R11 may be the same or different and are selected from the group consisting of hydrogen, halogen, amino, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms and phenyl (optionally substituted by halogen or C1-C4-alkyl), or A represents a heterocycle of the formula (Het-3) in which R12 is selected from the group consisting of halogen, C1-C4-alkyl and C1-C4-halogenoalkyl having 1 to 5 halogen atoms, and R13 is selected from the group consisting of hydrogen, C1-C4-alkyl and C1-C4-halogenoalkyl having 1 to 5 halogen atoms, or A represents a heterocycle of the formula (Het-4) in which R14 and R15 may be the same or different and are selected from the group consisting of hydrogen, halogen, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms, —S—C1-C4-alkyl, —S(O)2—C1-C4-alkyl, phenyl optionally substituted by halogen or C1-C4-alkyl and pyridyl (optionally substituted by halogen or C1-C4-alkyl), and R16 is selected from the group consisting of hydrogen, halogen, cyano, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms and C1-C4-halogenoalkoxy having 1 to 5 halogen atoms, or A represents a heterocycle of the formula (Het-5) in which R17 and R18 may be the same or different and are selected from the group consisting of hydrogen, halogen, C1-C4-alkyl, C1-C4-alkyloxy and C1-C4-halogenoalkyl having 1 to 5 halogen atoms, and R19 is selected from the group consisting of hydrogen, halogen, C1-C4-alkyl and C1-C4-halogenoalkyl having 1 to 5 atoms, or A represents a heterocycle of the formula (Het-6) in which R20 is selected from the group consisting of hydrogen, halogen, cyano, C1-C4-alkyl and C1-C4-halogenoalkyl having 1 to 5 halogen atoms, and R21 and R23 may be the same or different and are selected from the group consisting of hydrogen, halogen, C1-C4-alkyl and C1-C4-halogenoalky having 1 to 5 halogen atoms, and R22 is selected from the group consisting of hydrogen, cyano, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms, C1-C4-alkoxy-C1-C4-alkyl, hydroxyl-C1-C4-alkyl, —S(O)2—C1-C4-alkyl, —S(O)2—N(C1-C4-alkyl)2, C1-C6-alkylcarbonyl, —S(O)2-phenyl (optionally substituted by halogen or C1-C4-alkyl) and benzoyl (optionally substituted by halogen or C1-C4-alkyl), or A represents a heterocycle of the formula (Het-7) in which R24 is selected from the group consisting of hydrogen, cyano, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms, C1-C4-alkoxy-C1-C4-alkyl, hydroxy-C1-C4-alkyl, —S(O)2—C1-C4-alkyl, —S(O)2—N(C1-C4-alkyl)2, C1-C6-alkylcarbonyl, —S(O)2-phenyl (optionally substituted by halogen or C1-C4-alkyl) and benzoyl (optionally substituted by halogen or a C1-C4-alkyl), and R25, R26 and R27 may be the same or different and are selected from the group consisting of hydrogen, halogen, cyano, C1-C4-alkyl, C1-C4-halogenalkyl having 1 to 5 halogen atoms and C1-C4-alkylcarbonyl, or A represents a heterocycle of the formula (Het-8) in which R28 is selected from the group consisting of hydrogen and C1-C4-alkyl, and R29 is selected from the group consisting of halogen, C1-C4-alkyl and C1-C4-halogenoalkyl having 1 to 5 halogen atoms, or A represents a heterocycle of the formula (Het-9) in which R30 is selected from the group consisting of hydrogen and C1-C4-alkyl, and R31 is selected from the group consisting of halogen, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms and phenyl (optionally substituted by halogen or C1-C4-alkyl), or A represents a heterocycle of the formula (Het-10) in which R32 is selected from the group consisting of hydrogen, halogen, amino, cyano, C1-C4-alkylamino, di-(C1-C4-alkyl)amino, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms and phenyl (optionally substituted by halogen or C1-C4-alkyl), and R33 is selected from the group consisting of halogen, C1-C4-alkyl and C1-C4-halogenoalkyl having 1 to 5 halogen atoms, C1-C5-halogenoalkoxy having 1 to 9 halogen atoms, amino, substituted or unsubstituted C1-C5-alkylamino or substituted or unsubstituted di-(C1-C5-alkyl)-amino, or A represents a heterocycle of the formula (Het-11) in which R34 is selected from the group consisting of hydrogen, halogen, amino, cyano, C1-C4-alkylamino, di-(C1-C4-alkyl)amino, C1-C4-alkyl and C1-C4-halogenoalkyl having 1 to 5 halogen atoms, and R35 is selected from the group consisting of halogen, C1-C4-alkyl and C1-C4-halogenoalkyl having 1 to 5 halogen atoms, or A represents a heterocycle of the formula (Het-12) in which R36 is selected from the group consisting of hydrogen, halogen, cyano, nitro, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms, C3-C6-cycloalkyl, C1-C4-alkoxy, C1-C4-halogenoalkoxy having 1 to 5 halogen atoms, —S—C1-C4-alkyl, —S(O)—C1-C4-alkyl, —S(O)2—C1-C4-alkyl, —S—C1-C4-halogenoalkyl having 1 to 5 halogen atoms, aminocarbonyl and aminocarbonyl-C1-C4-alkyl, and R37 is selected from the group consisting of hydrogen, halogen, cyano, nitro, C1-C4-alkyl, C1-C4-alkoxy, —S—C1-C4-alkyl, —S(O)—C1-C4-alkyl, and —S(O)2—C1-C4-alkyl, and R38 is selected from the group consisting of hydrogen, phenyl, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms, hydroxy-C1-C4-alkyl, C2-C6-alkenyl, C3-C6-cycloalkyl, C1-C4-alkylthio-C1-C4-alkyl, C1-C4-alkyl-S(O)—C1-C4-alkyl, C1-C4-alkyl-S(O)2—C1-C4-alkyl, C1-C4-halogenoalkylthio-C1-C4-alkyl having 1 to 5 halogen atoms, C1-C4-alkoxy-C1-C4-alkyl and C1-C4-halogenoalkoxy-C1-C4-alkyl having 1 to 5 halogen atoms, or A represents a heterocycle of the formula (Het-13) in which R39 is selected from the group consisting of hydrogen, halogen, cyano, nitro, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms, C3-C6-cycloalkyl, C1-C4-alkoxy, C1-C4-halogenoalkoxy having 1 to 5 halogen atoms, —S—C1-C4-alkyl, S(O)—C1-C4-alkyl, —S(O)2—C1-C4-alkyl, —S—C1-C4-halogenoalkyl having 1 to 5 atoms, aminocarbonyl and aminocarbonyl-C1-C4-alkyl, and R40 is selected from the group consisting of hydrogen, halogen, cyano, C1-C4-alkyl, C1-C4-alkoxy, C1-C4-halogenoalkoxy having 1 to 5 halogen atoms, —S—C1-C4-alkylS(O)—C1-C4-alkyl, and —S(O)2—C1-C4-alkyl, and R41 is selected from the group consisting of hydrogen, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms, hydroxy-C1-C4-alkyl, C2-C6-alkenyl, C3-C6-cycloalkyl, C1-C4-alkylthio-C1-C4-alkyl, C1-C4-alkyl-S(O)—C1-C4-alkyl, C1-C4-alkyl-S(O)2—C1-C4-alkyl, C1-C4-halogenoalkylthio-C1-C4-alkyl having 1 to 5 halogen atoms, C1-C4-alkoxy-C1-C4-alkyl, C1-C4-halogenoalkoxy-C1-C4-alkyl having 1 to 5 halogen atoms and phenyl (optionally substituted by halogen, C1-C4-alkyl, C1-C4-alkoxy-C1-C4-alkyl or nitro), or A represents a heterocycle of the formula (Het-14) in which R42 is selected from the group consisting of hydrogen, halogen, cyano, nitro, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms, C3-C6-cycloalkyl, C1-C4-alkoxy, C1-C4-halogenoalkoxy having 1 to 5 halogen atoms, —S—C1-C4-alkyl, S(O)—C1-C4-alkyl, —S(O)2—C1-C4-alkyl, —S—C1-C4-halogenoalkyl having 1 to 5 halogen atoms, aminocarbonyl and aminocarbonyl-C1-C4-alkyl, and R43 is selected from the group consisting of hydrogen, halogen, cyano, C1-C4-alkyl, C1-C4-alkoxy, —S—C1-C4-alkyl, S(O)—C1-C4-alkyl, —S(O)2—C1-C4-alkyl, and C1-C4-halogenoalkyl having 1 to 5 halogen atoms, and R44 is selected from the group consisting of hydrogen, phenyl, benzyl, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms, hydroxy-C1-C4-alkyl, C2-C6-alkenyl, C3-C6-cycloalkyl, C1-C4-alkylthio-C1-C4-alkyl, C1-C4-alkyl-S(O)—C1-C4-alkyl, C1-C4-alkyl-S(O)2—C1-C4-alkyl, C1-C4-halogenoalkylthio-C1-C4-alkyl having 1 to 5 halogen atoms, C1-C4-alkoxy-C1-C4-alkyl and C1-C4-halogenoalkoxy-C1-C4-alkyl having 1 to 5 halogen atoms, or A represents a heterocycle of the formula (Het-15) in which R45 and R46 may be the same or different and are selected from the group consisting of hydrogen, halogen, C1-C4-alkyl and C1-C4-halogenoalkyl having 1 to 5 halogen atoms, or A represents a heterocycle of the formula (Het-16) in which R47 and R48 may be the same or different and are selected from the group consisting of hydrogen, halogen, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms, phenyl (optionally substituted by halogen or a C1-C4-alkyl), and heterocyclyl like pyridyl, pyrimidinyl and thiadiazolyl (each optionally substituted by halogen or C1-C4-alkyl), or A represents a heterocycle of the formula (Het-17) in which R49 and R50 may be the same or different and are selected from the group consisting of hydrogen, halogen, C1-C4-alkyl and C1-C4-halogenoalkyl having 1 to 5 halogen atoms, or A represents a heterocycle of the formula (Het-18) in which R51 is selected from the group consisting of halogen, C1-C4-alkyl and C1-C4-halogenoalkyl having 1 to 5 halogen atoms, or A represents a heterocycle of the formula (Het-19) in which R52 is selected from the group consisting of halogen, C1-C4-alkyl and C1-C4-halogenoalkyl having 1 to 5 halogen atoms, and R53 is selected from the group consisting of hydrogen, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms and phenyl (optionally substituted by halogen or C1-C4-alkyl), or A represents a heterocycle of the formula (Het-20) in which R54 is selected from the group consisting of halogen, C1-C4-alkyl and C1-C4-halogenoalkyl having 1 to 5 halogen atoms, or A represents a heterocycle of the formula (Het-21) in which R55 is selected from the group consisting of hydrogen, halogen, hydroxy, cyano, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms, C1-C4-alkoxy, —S—C1-C4-alkyl, S(O)—C1-C4-alkyl, —S(O)2—C1-C4-alkyl, —S—C1-C4-halogenoalkyl having 1 to 5 halogen atoms and C1-C4-halogenoalkoxy having 1 to 5 halogen atoms, and R56, R57 and R58, which may be the same or different, are selected from the group consisting of hydrogen, halogen, cyano, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms, C1-C4-alkoxy, —S—C1-C4-alkyl, C1-C4-halogenoalkoxy having 1 to 5 halogen atoms, —S(O)—C1-C4-alkyl and S(O)2—C1-C4-alkyl, or A represents a heterocycle of the formula (Het-22) in which R59 is selected from the group consisting of hydrogen, halogen, hydroxy, cyano, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms, C1-C4 alkoxy, —S—C1-C5-alkyl, S(O)—C1-C4-alkyl, —S(O)2—C1-C4-alkyl, —S—C2-C5-alkenyl, —S—C1-C4-halogenoalkyl having 1 to 5 halogen atoms, C1-C4-halogenoalkoxy having 1 to 5 halogen atoms, phenyloxy (optionally substituted by halogen or C1-C4-alkyl) and —S-phenyl (optionally substituted by halogen or C1-C4-alkyl), and R60, R61 and R62, which may the same or different, are selected from the group consisting of hydrogen, halogen, cyano, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms, C1-C4-alkoxy, —S—C1-C4-alkyl, C1-C4-halogenoalkoxy having 1 to 5 halogen atoms, —S(O)—C1-C4-alkyl, —S(O)2—C1-C4-alkyl, N-morpholine optionally substituted by halogen or C1-C4-alkyl, and thienyl (optionally substituted by halogen or a C1-C4-alkyl), or A represents a heterocycle of the formula (Het-23) in which R63, R64, R65 and R66, which may be the same or different, are selected from the group consisting of hydrogen, halogen, hydroxy, cyano, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms, C1-C4-alkoxy, —S—C1-C4-alkyl, —S—C1-C4-halogenoalkyl having 1 to 5 halogen atoms, C1-C4-halogenoalkoxy having 1 to 5 halogen atoms, —S(O)—C1-C4-alkyl and S(O)2—C1-C4-alkyl, or A represents a heterocycle of the formula (Het-24) in which R67 is selected from the group consisting of hydrogen, halogen, C1-C4-alkyl and C1-C4-halogenoalkyl having 1 to 5 halogen atoms, and R68 is selected from the group consisting of hydrogen, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms, C1-C6-alkoxycarbonyl, benzyl (optionally substituted by 1 to 3 halogen atoms), benzyloxycarbonyl (optionally substituted by 1 to 3 halogen atoms), and heterocyclyl like pyridyl and pyrimidinyl (each optionally substituted by halogen, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms), or A represents a heterocycle of the formula (Het-25) in which R69 is selected from the group consisting of hydrogen, halogen, hydroxy, cyano, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms, C1-C4-alkoxy, —S—C1-C4-alkyl, —S—C1-C4-halogenoalkyl having 1 to 5 halogen atoms and C1-C4-halogenoalkoxy having 1 to 5 halogen atoms, and R70 is selected from the group consisting of hydrogen, C1-C4-alkyl, C1-C4-halogenoalkyl having 1 to 5 halogen atoms, and benzyl, or A represents a heterocycle of the formula (Het-26) in which X1 is selected from the group consisting of sulphur, —SO—, —SO2— and CH2—, and R71 is selected from the group consisting of C1-C4-alkyl and C1-C4-halogenoalkyl having 1 to 5 halogen atoms, and R72 and R73 may be the same or different and are selected from the group consisting of hydrogen and C1-C4-alkyl, or A represents a heterocycle of the formula (Het-27) in which R74 is selected from the group consisting of C1-C4-alkyl and C1-C4-halogenoalkyl having 1 to 5 halogen atoms, or A represents a heterocycle of the formula (Het-28) in which R75 is selected from the group consisting of C1-C4-alkyl and C1-C4-halogenoalkyl having 1 to 5 halogen atoms, or A represents a heterocycle of the formula (Het-29) in which R76 is selected from the group consisting of hydrogen, halogen, C1-C4-alkyl and C1-C4-halogenoalkyl having 1 to 5 halogen atoms.
地址 Leverkusen DE