发明名称 |
Method for quantifying optical properties of the human lens |
摘要 |
Method for quantifying optical properties of the human lens. The present invention includes the application of fiberoptic, OMA-based instrumentation as an in vivo diagnostic tool for the human ocular lens. Rapid, noninvasive and comprehensive assessment of the optical characteristics of a lens using very modest levels of exciting light are described. Typically, the backscatter and fluorescence spectra (from about 300- to 900-nm) elicited by each of several exciting wavelengths (from about 300- to 600-nm) are collected within a few seconds. The resulting optical signature of individual lenses is then used to assess the overall optical quality of the lens by comparing the results with a database of similar measurements obtained from a reference set of normal human lenses having various ages. Several metrics have been identified which gauge the optical quality of a given lens relative to the norm for the subject's chronological age. These metrics may also serve to document accelerated optical aging and/or as early indicators of cataract or other disease processes.
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申请公布号 |
US5894340(A) |
申请公布日期 |
1999.04.13 |
申请号 |
US19960744678 |
申请日期 |
1996.11.06 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
LOREE THOMAS R.;BIGIO, IRVING J.;ZUCLICH, JOSEPH A.;SHIMADA, TSUTOMU;STROBL, KARLHEINZ |
分类号 |
A61B3/117;(IPC1-7):A61B3/00 |
主分类号 |
A61B3/117 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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