发明名称 Epothilone derivatives and methods for making and using the same
摘要 This invention relates to compounds of formula (I) and to pharmaceutically acceptable salts and solvates thereof, wherein R<1>, R<2>, R<3>, R<4>, R<5>, W, X, Y, and Ar are as defined herein. Compounds of formula (I) are useful in the treatment of diseases or conditions characterized by cellular hyperproliferation. This invention also relates to means for the preparation of compounds of Formula (I); formulations containing compounds of formula (I); and methods for the use of said compounds and formulations in the treatment of a disease or condition characterized by cellular hyperproliferation, including cancer.
申请公布号 AU2002338336(A1) 申请公布日期 2002.10.21
申请号 AU20020338336 申请日期 2002.04.02
申请人 KOSAN BIOSCIENCES, INC. 发明人 LI TANG;ROBERT L. ARSLANIAN;BRIAN METCALF;JOHN CARNEY;GARY ASHLEY
分类号 C07D313/00;C07D405/06;C07D413/06;C07D417/06;C07D491/04;C12N1/20;C12N9/00;C12N15/52;C12N15/74;C12P17/16;C12P17/18 主分类号 C07D313/00
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