| 发明名称 | Antibody to a carbonic anhydrase | ||
| 摘要 | The present invention relates to an antibody binding to a carbonic anhydrase, wherein the antibody comprises (a) the amino acid sequences SEQ ID NOS. 1 (CDR 1), 2 (CDR 2) and 3 (CDR 3) determining the CDRs of the VH region, and the amino acid sequences SEQ ID NOS. 4 (CDR 1), 5 (CDR 2) and 6 (CDR 3) determining the CDRs of the VL region; or (b) the amino acids sequences of (a), wherein at least one amino acid is conservatively substituted in any one of the amino acid sequences SEQ ID NOS. 1 to 6. | ||
| 申请公布号 | US9359446(B2) | 申请公布日期 | 2016.06.07 |
| 申请号 | US201113696011 | 申请日期 | 2011.05.02 |
| 申请人 | Hemholtz Zentrum Munchen—Deutches Forschungszentrum Fur Gesundheit Und Umwelt (GmbH) | 发明人 | Zeidler Reinhard;Battke Christina;Kremmer Elisabeth;Flatley Andrew;Supuran Claudiu |
| 分类号 | A61K39/395;C07K16/40;C07K16/30 | 主分类号 | A61K39/395 |
| 代理机构 | Briggs and Morgan, P.A. | 代理人 | Briggs and Morgan, P.A. ;Babcock Audrey J. |
| 主权项 | 1. An antibody binding to a carbonic anhydrase, wherein the antibody comprises: the amino acid sequences SEQ ID NOS: 1 (CDR 1), 2 (CDR 2) and 3 (CDR 3) determining the CDRs of the VH region, and the amino acid sequences SEQ ID NOS: 4 (CDR 1), 5 (CDR 2) and 6 (CDR 3) determining the CDRs of the VL region. | ||
| 地址 | Neuherberg DE | ||